EU-funded research
PREDICTOM
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Our Science
Science,notguesswork.
Ten years of genetic and epigenetic research, turned into guidance you can act on every day.
Two kinds of insight
“Your DNA is the script you were born with. Your lifestyle is the director.”
DNA
What you were born with
Your genetic code stays the same for life. A DNA test reads 150+ results across 23 report areas, showing how your body tends to handle food, nutrients, training, sleep and stress.
- Test once, for life
- Diet, vitamins, fitness, sleep, stress and more
- Shapes your plan and MAISIE's advice
Epigenetics
What you can change
Epigenetics looks at chemical markers that switch genes on or off. They change with your diet, stress, exercise, sleep and environment, so you can measure how your habits are working.
- Epigenetic Body Age, plus hearing, eye and memory age
- Immune, inflammation and muscle scores
- Retest to track change
Research we're part of
Science in the real world.
The projects and partnerships behind Muhdohub.
EU-funded research
AccessAD
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Partnership
Caribbean Genome Project
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Published research
Read the papers.
Saliva-based epigenetics, built on Muhdo’s own dataset and published for anyone to check. Every link goes to the paper itself.
10 methylation sites · one saliva sample
3peer-reviewed papers on saliva DNA methylation
3,408healthy people in the training data for our 10-site clock
898women in the independent validation study
10methylation sites in our published saliva clock
Sample sizes are as reported in the papers below. Findings describe groups of people, not individual results. Guidance, not a diagnosis.
Peer-reviewed
Peer-reviewed
Peer-reviewed
Peer-reviewed
A Cost-Effective Saliva-Based Human Epigenetic Clock Using 10 CpG Sites Identified with the Illumina EPIC 850k Array
Shows that a saliva clock can be built from just 10 methylation sites, trained on 3,408 healthy people aged 15 to 89.
3,408 peopleAges 15 to 8910 sites
Collins, Brown and Chung
Read the paperdoi:10.3390/dna5020028
Independent Female-Cohort Recalibration of a 10-CpG Saliva Epigenetic Clock: Age-Adjusted Phenotype Associations
An independent check of the same 10-site clock in 898 women aged 12 to 85, run with the University of Essex. All 10 sites stayed linked to age, and the data is deposited with the UK Data Service.
898 womenAges 12 to 85With the University of Essex
Collins and colleagues
Read the paperdoi:10.3390/biomedicines14112491
MMS-32: Development and Evaluation of a 32-CpG Salivary DNA Methylation Score Associated with Subjective Memory Ratings in Males
A 32-site saliva score linked to how men rate their own memory, built from large comparisons of Muhdo saliva samples on the EPIC array.
32 sitesMemoryMales
Collins and Ajaz
Read the paperdoi:10.3390/dna6040050
More from the science team
Earlier work and preprints.
Preprints are shared before peer review, so they are labelled as preprints. Each link opens the original.
- MuhdoAge: a novel saliva-based epigenetic clockCollins, Brown and Berkley · healthy cohort of 1,844 peoplePreprint · not peer-reviewedRead the preprint
- High-intensity exercise and sport type are associated with lower epigenetic biological age in middle-aged menCollinsPreprint · not peer-reviewedRead the preprint
- High-intensity resistance training is associated with epigenetic reprogramming & distinct salivary DNA methylation patternsCollinsPreprint · not peer-reviewedRead the preprint
- Creatine monohydrate use is associated with performance-enhancing DNA methylation patternsCollinsPreprint · not peer-reviewedRead the preprint
- DNA methylation on PPARG and its relation to sports injury and pain in male football (soccer) players at all levelsCollinsPreprint · not peer-reviewedRead the preprint
- Resistance training, recovery and genetics: AMPD1 the gene for recoveryCollinsJournal articleRead the paper
- Can genetics predict sports injury? The association of the genes GDF5, AMPD1, COL5A1 and IGF2 on soccer player injury occurrenceMcCabe and CollinsJournal articleRead the paper
- Born equal: Can genetics make the perfect athlete?CollinsPreprint · not peer-reviewedRead the preprint
Open science
Our clocks and data are open to check.
We release our work on public repositories, under open licences, so other researchers can test it independently.
Collins_MH400 Age Clock v1.0.0
A ready-to-use saliva DNA methylation clock, released for anyone to try and check.
CollinsOpen on Zenododoi:10.5281/zenodo.22811856
Collins geriatric methylation (DNA) saliva clock
Another ready-to-use saliva clock built from the Muhdo dataset, also released openly.
CollinsOpen on Zenododoi:10.5281/zenodo.23478688
Female cohort study: DNA methylation, a 10-CpG epigenetic data and questionnaire phenotype, 2018–2024
The dataset behind the independent female-cohort paper, deposited for other researchers to use.
Collins and ChungOpen the datasetdoi:10.5255/UKDA-SN-858771
For clinics, practitioners and partners
Science and Education 2026
Our full science and education pack, in one document.
Download the PDFContent needed: the PDF file