The 10-CpG epigenetic clock (Collins et al. 2025) is a breakthrough in biological age testing, offering precise insights into how your body is ageing at a molecular level using just ten carefully selected DNA methylation markers. Unlike traditional clocks that require hundreds of markers and are costly to run, this saliva-based test is non-invasive, affordable, and highly accurate (correlation r ≈ 0.80) improving in very healthy subject. It captures subtle, real-time biological changes that chronological age alone can’t reveal, making it a powerful tool for preventative health and personalised wellness planning.
Recent findings show how lifestyle, health status, and major life events accelerate or decelerate biological age. For example, heavy alcohol consumption is linked to being biologically eight years older than peers, while late pregnancy temporarily accelerates ageing by around 3–4 years. Chronic illnesses such as dementia, fatigue, fibromyalgia, and cancer show 8–12 years of age acceleration, highlighting the test’s ability to identify hidden biological stress long before symptoms arise. These results make the 10-CpG clock a game-changing biomarker for tracking health span, risk factors, and recovery.
Testing your biological age with the 10-CpG clock empowers you to take control of your health. By uncovering how your lifestyle choices, stress, and environment are affecting your body, you can take targeted action to slow or even reverse epigenetic ageing through nutrition, exercise, and personalised interventions. Whether you’re focused on longevity, early detection of health risks, or simply optimising your well-being, this test gives you clear, actionable insights to make better health decisions now and protect your future.
The 10-CpG clock is a published, validated clock and is used to determine your biological (predicted age) and methylpace result.
References
Collins, C.; Brown, J.; Chung, H.C. A Cost-Effective Saliva-Based Human Epigenetic Clock Using 10 CpG Sites Identified with the Illumina EPIC 850k Array. DNA 2025, 5, 28. https://doi.org/10.3390/dna5020028
Collins, C.; Puras, A. Biological Age vs. Disease using the 10-CpG Clock. Encyclopedia. Available online: https://encyclopedia.pub/entry/58863 (accessed on 01 September 2025).
